New algorithm improves ability to generate better genetic predictors

Researchers now have a new, more refined tool, the Polygenic-Risk-Score (PRS) on Spark, to help them understand an individual’s genetic risk for common illnesses, including mental illnesses. In an initial validation study, the newly developed software package successfully generated a polygenic risk score for a cohort of Canadian women that explained and predicted more of […]

Molecular proof – Teen brain impacted by environment

A new study in mice provides molecular-level proof that the environment we are raised in continues to exert significant influence on brain development beyond childhood into adolescence. The study, published in Nature Communications, demonstrated that the environment in which an adolescent is raised causes measurable epigenetic modifications that influence which genes are activated or muted […]

Cell morphology might relate to differences in maternal behaviour

New research provides insight into how a profound remodeling of cell morphology in a specific brain region —the medial preoptic area (MOPA)— might relate to individual differences in maternal behavior. Both pregnancy hormones and pup sensory stimuli increase neuronal activation leading to a remodeling of neuronal circuits within certain brain regions, including the MPOA, that […]