Ludmer Centre Scientific Director Celia Greenwood secured over $600K in funding for new research, Precision Medicine in Cellular Epigenomic, from the recent Genome Canada competitions. To understand brain development, researchers need to unlock the secrets of our DNA. Currently, we can collect data on multiple aspects of DNA, but to extract meaning from the ever-expanding data trove requires the right […]
When it comes to maternal mental health, sadly, Canada lags behind other countries, like Australia and the UK, where pre- and post-natal mental health are subject to regular screening. Listen to CTV’s News at Noon, where Dr Kieran O’Donnell discussed the impact of prenatal anxiety and depression on the mother’s and the child’s long-term mental health with news […]
Those administering policies that separate children from their parents clearly don’t understand the effects of early childhood trauma on the developing brain. In an interview with Quirks & Quarks host Bob McDonald, Dr Michael Meaney explains how parents insulate their children from stresses while their brains mature. When children are traumatically separated from parents their brain is forced to […]
Since arriving at McGill and the Montreal Neurological Institute and Hospital more than 30 years ago, Alan Evans has helped the University and its network of affiliated hospitals build one of the world’s largest infrastructures of neuroscience research – from the high-resolution Big Brain atlas to supercomputing data-storage technology. These developments and others by his fellow researchers […]
Eczema may be an early warning sign for potential mental health problems. According to Dr Patricia P Silveira, “When treating young girls for childhood cutaneous allergies, such as eczema, healthcare professionals should be aware of the increased potential for vulnerability for mental health problems. Understanding and investigating these types of associated risks is crucial to […]
A new study in mice provides molecular-level proof that the environment we are raised in continues to exert significant influence on brain development beyond childhood into adolescence. The study, published in Nature Communications, demonstrated that the environment in which an adolescent is raised causes measurable epigenetic modifications that influence which genes are activated or muted […]
A new study shows that childhood adversity can get ‘under the skin’ and influence epigenetic markers in our blood. Interestingly, the study also suggests for the first time, that perinatal interventions, that tackle early adversity, might have similar effects. The findings are based on a 30-year trial of the Nurse-Family Partnership (NFP), which has shown […]
The long-term consequences of poor infant nutrition, particularly in the first weeks after birth, are becoming clearer thanks to a new study. Preterm, underweight babies who benefited from a higher energy intake –specifically more protein and fats- during the first three weeks of life had healthier body weights in their 20s (as measured by a […]
Moving beyond the overly simplistic unhealthy lifestyle paradigm, researchers are slowly uncovering the genetic and epigenetic mechanisms behind obesity. Recent research by Ludmer Centre researcher Dr Patricia P Silveira at McGill and the Douglas Institute and her colleagues has shown that altered dopamine signaling may increase a preference for more palatable high-sugar foods leading to a risk […]
How does childhood stress establish the groundwork for adult depression? Researchers at the Icahn School of Medicine at Mount Sinai and Ludmer researcher Dr Rose Bagot found genes regulated by the transcription factor OTX2 – a protein controlling the rate of transcription of genetic information from DNA to messenger RNA – primed the response toward […]