Child’s genetic profil & maternal depression

A new study underscores the importance of identifying and preventing prenatal symptoms of depression to prevent the development of childhood psychopathology. The study utilized the Ludmer Centre’s longitudinal cohort study, MAVAN, and involved four of its researchers Michael J. Meaney, John Lydon, Helene Gaudreau, Ashley Wazana as well as other collaborators, including first author Cathryn Gordon-Green. The study suggests that maternal prenatal symptoms of depression and a child’s multilocus genetic profile (phenotype/traits influenced by multiple genes) interact to predict early age negative emotionality from 3 to 36 months of age. These unique findings are also strengthened by the design of the study: prenatal longitudinal data across multiple time points and complimentary and complimentary [mixed-model regression] and novel analyses [confirmatory analysis]. Read more