Better understanding of differences in susceptibility & resilience to chronic stress

In the first study to use ex vivo structural MRI and DTI to detect differences in local-brain-volume and tissue-diffusion properties associated with stress susceptibility/resilience, a team of researchers from Canada, USA and Singapore, including Ludmer Centre researchers (Meaney, O’Donnell, Bagot), found that stress-integrative brain regions shape the neural architecture underlying individual differences in susceptibility/resilience to […]

Canadian Institutes of Health Research Grant

To advance mental health research, the Centre participates in multidisciplinary research cadres globally to maximize its neuroinformatics infrastructure and longitudinal cohort study MAVAN. Supported by a CIHR Grant, the Centre’s statistical genetics and epigenetics expertise and Dr Ashley Wazana’s team of researchers hope, in the next 5 years, to identify psychiatric diagnoses at age 13 […]

Child’s genetic profil & maternal depression

A new study underscores the importance of identifying and preventing prenatal symptoms of depression to prevent the development of childhood psychopathology. The study utilized the Ludmer Centre’s longitudinal cohort study, MAVAN, and involved four of its researchers Michael J. Meaney, John Lydon, Helene Gaudreau, Ashley Wazana as well as other collaborators, including first author Cathryn […]

Neuroscience is global!

The Ludmer Centre hosted Dr Pedro A. Valdes-Sosa, Director of the Joint China-Cuba Lab for Frontiers Research in Translational Neurotechnology in Chengdu (China) and Vice Director of Research at the Cuban Neuroscience Center in Habana (Cuba). During his visit, Dr Valdes-Sosa presented his latest research : “Matrix-Tensor network methods for Brain Connectivity” and “Multimodal quantitative […]

Genetic variant in a sea of DNA: MURAT

Identifying rare variants in health and disease is the goal of many genetic studies.  Phenotypes associated with the disease sometimes include many physiological measures.  Many times these measures are themselves correlated adding to the complexity of multiple testing.  Celia Greenwood, Scientific Director of the Ludmer Centre, and a team of researchers have developed of a […]

EMC donation to the neuroinformatics component

EMC Corp provides major boost to the Ludmer Centre’s neuroinformatics component – the McGill Centre for Integrative Neuroscience (MCIN) led by Dr Alan Evans. The $1M in state-of-the-art visualization and data-storage technology will allow researchers worldwide to store, protect, share and analyze their most valuable asset: information. According to Mike Sharun, EMC Canada country manager, […]

Ludmer Centre research: innovative & cutting edge

Revolutionizing mental health research Until recently, we lacked the technology to adequately study the living brain in all its complexities; however, new research and technologies, pioneer by Ludmer Centre researchers, have resulted in significant advancements in the fields of genetic mapping, brain imaging and epigenetics, among others. The next decade will be marked by an […]

Progress hampered by symptom-based diagnosis

Progress remains limited Everything we know about mental illness, from diagnosis to treatment, begins with a symptom-based checklist. Imagine being diagnosed with cancer based on an interview examination, then being told there is no test to confirm the diagnosis nor to determine which treatment approach is optimal for you. Despite the magnitude and growing recognition of […]

Mental illness, no one is untouched

There are over 400 mental disorders —from depression to Alzheimer’s to attention deficit disorders— yet there are no biological tests to confirm a diagnosis, only subjective behavioral-based tests and, in a few cases, post-mortem confirmation through brain tissue analyses. Imagine if we could diagnose those at risk of developing a mental illness before symptoms started, if we could prevent […]