Women in Science @ the Ludmer Centre

It’s no secret; globally sexism continues to prevail within business, academia and research, particularly, in STEM fields — science, technology, engineering and math. The theme of the 2018 United Nations’ International Day of Women and Girls in Science on February 11th is ‘Equality and Parity in Science’. On March 8th, International Women’s Day builds on this with […]

How mathematical modeling helps decipher the brain’s ‘black box’

Mathematical modeling is key to understanding the complex processes underpinning protein misfolding and neurological diseases. Correctly folded, proteins play a central role in the structure, function, and regulation of the body’s tissues and organs, including the brain. Abnormal or misfolded proteins, in multiple studies, are increasingly associated with conditions such as Prion diseases, Alzheimer’s disease, […]

Eczema, an early warning sign for potential mental illness

Eczema may be an early warning sign for potential mental health problems. According to Dr Patricia P Silveira, “When treating young girls for childhood cutaneous allergies, such as eczema, healthcare professionals should be aware of the increased potential for vulnerability for mental health problems. Understanding and investigating these types of associated risks is crucial to […]

Canada-Cuba-China partnership gets $1M to study Alzheimer’s

Alzheimer’s and dementia research just got a significant boost from a tripartite Canada-Cuba-China research collaboration. Ludmer Centre Scientific Director Dr Alan Evans is part of an international team that just received $1 M in financial support over three years to initiate the first scientific collaboration on brain imaging and neuroinformatics among leading neuroscience researchers in Canada, […]

Alzheimer’s & Dementia Research @ the Ludmer Centre

Big-data in Dementia Research Dementias affect millions of people across Canada (right) and 46.8 million people worldwide – a number set to double every 20 years (WHO, 2015). The most common cause of dementia, late-onset Alzheimer’s disease, is not caused by a single neurological mechanism but is the product of several associated brain mechanisms influenced […]

Molecular proof – Teen brain impacted by environment

A new study in mice provides molecular-level proof that the environment we are raised in continues to exert significant influence on brain development beyond childhood into adolescence. The study, published in Nature Communications, demonstrated that the environment in which an adolescent is raised causes measurable epigenetic modifications that influence which genes are activated or muted […]

Childhood experiences gets under the skin: for better and worse

A new study shows that childhood adversity can get ‘under the skin’ and influence epigenetic markers in our blood. Interestingly, the study also suggests for the first time, that perinatal interventions, that tackle early adversity, might have similar effects. The findings are based on a 30-year trial of the Nurse-Family Partnership (NFP), which has shown […]

Dr Alan Evans among 2017 Highly Cited Researchers

  Congratulations to Dr Alan Evans.  Clarivate Analytics once again ranked him among the most Highly Cited Researchers in Neuroscience and Behavior, a ranking he has maintained annually since in 2014. Three other McGill Univeristy researchers also made the top 1% ranking: Dr Mark Lathrop in Molecular Biology and Genetics, Dr Chao-Jun Li in Chemistry, and […]

Sugar cravings may be due to dopamine dysfunction

Moving beyond the overly simplistic unhealthy lifestyle paradigm, researchers are slowly uncovering the genetic and epigenetic mechanisms behind obesity. Recent research by Ludmer Centre researcher Dr Patricia P Silveira at McGill and the Douglas Institute and her colleagues has shown that altered dopamine signaling may increase a preference for more palatable high-sugar foods leading to a risk […]